How can mechanical stresses affect peripheral nerves compared to dorsal root ganglion?

The correct choice highlights the greater sensitivity of dorsal root ganglia (DRG) to mechanical stimulation compared to peripheral nerves. Dorsal root ganglia contain the cell bodies of sensory neurons and are situated in close proximity to structures that can generate mechanical stress. This anatomical placement, combined with the specific molecular and cellular characteristics of the neurons within the DRG, makes them more susceptible to changes in mechanical conditions, such as compression or stretch.

In contrast, peripheral nerves are composed of many axons surrounded by supportive tissues and are generally designed to withstand mechanical stress functions, such as movement and stretching of the limbs. While peripheral nerves can certainly be affected by mechanical stresses, they tend to exhibit a degree of resilience that DRG do not have, resulting in a lower sensitivity to compression.

This understanding emphasizes the need for chiropractic applications to consider both peripheral nerve pathways and dorsal root ganglion in the evaluation and treatment of nerve-related symptoms, acknowledging that different segments of the nervous system may respond differently under similar mechanical conditions.